MTHFR Polymorphisms - What You Need to Know

Apr 26, 2020


Welcome to Flatirons Integrative Health & Nutrition, the leading destination for comprehensive health information and solutions. We are dedicated to providing clients with the latest information and resources on various health topics, including MTHFR polymorphisms.

Understanding MTHFR Polymorphisms

MTHFR (methylenetetrahydrofolate reductase) is an enzyme responsible for converting folate (vitamin B9) into its active form, which is essential for various bodily processes. However, certain genetic variations or polymorphisms in the MTHFR gene can impact the enzyme's function.

These polymorphisms can affect the body's ability to convert folate into its active form, leading to potential health implications. Two common polymorphisms are known as C677T and A1298C, each with varying levels of impact on enzyme activity.

The Impact of MTHFR Polymorphisms

Individuals with MTHFR polymorphisms may experience a range of health concerns, including:

  • Cardiovascular Health: Research suggests a potential link between MTHFR polymorphisms and an increased risk of cardiovascular diseases, such as heart disease and stroke.
  • Mental Health: Some studies indicate a possible association between MTHFR polymorphisms and mental health disorders like depression, anxiety, and bipolar disorder.
  • Pregnancy Complications: MTHFR polymorphisms may contribute to complications during pregnancy, such as recurrent pregnancy loss and preeclampsia.
  • Neurological Disorders: There is ongoing research exploring the connection between MTHFR polymorphisms and neurological disorders like autism, Alzheimer's disease, and migraines.
  • Detoxification: MTHFR polymorphisms may affect the body's ability to efficiently detoxify harmful substances, potentially influencing overall health and wellbeing.

Addressing MTHFR-Related Concerns

At Flatirons Integrative Health & Nutrition, we understand the importance of personalized care when it comes to MTHFR-related concerns. Our team of experts, led by Jenny Demeaux, RNC ND, specializes in integrative approaches to optimize health and address genetic variations.

We offer comprehensive assessments to identify and understand the impact of MTHFR polymorphisms on your health. Our tailored treatment plans focus on a combination of nutritional support, lifestyle modifications, and targeted supplementation to help you optimize your well-being.

Why Choose Flatirons Integrative Health & Nutrition?

When it comes to MTHFR polymorphisms and overall health optimization, Flatirons Integrative Health & Nutrition stands out for several reasons:

  1. Expertise: Our team consists of highly qualified professionals with extensive knowledge and expertise in addressing various genetic variations, including MTHFR polymorphisms.
  2. Personalized Approach: We understand that each individual is unique, and our treatment plans are tailored to meet your specific needs, considering your health history, genetic profile, and lifestyle factors.
  3. Evidence-Based Solutions: Our recommendations are based on the latest scientific research and medical literature, ensuring you receive accurate and reliable information.
  4. Comprehensive Care: We take a holistic approach to health and well-being, addressing not just MTHFR polymorphisms but also other contributing factors that may impact your overall health.
  5. Long-Term Support: Our commitment to your well-being extends beyond initial assessments and treatment plans. We provide ongoing support and guidance throughout your health journey.


If you suspect you have MTHFR polymorphisms or are interested in optimizing your health through personalized care, reach out to Jenny Demeaux, RNC ND, and the team at Flatirons Integrative Health & Nutrition. Together, we can help you better understand your genetic profile and develop strategies to promote your overall well-being.